N-Oxide as a Potential Function in the Design of Enzyme Inhibitors. Application to 2,3-Epoxysqualene-sterol Cyclases

DOI: 10.1039/c39850001054

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1054 - 1055 (1985)

Update date:2022-08-11

Topics:

Authors:

Cerutti, Maurizio

Delprino, Laura

Cattel, Luigi

Bouvier-Nave, Pierrette

Duriatti, Albert

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39850001054

The N-oxides of several tertiary amines possessing an aliphatic long chain are more potent inhibitors of 2,3-epoxysqualene-β-amyrin and -lanosterol cyclases than their parent amines.

Full text of DOI:10.1039/c39850001054

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:2-aza-2,3-dihydrosqualene N-oxide

Cas No:100692-38-4

R&D Labs maybe for 100692-38-4

Skyrun Industrial Co.,Ltd(expird)

website:http://www.chinaskyrun.com

Contact:0086-576-84610586

Address:Chemical Development Zone
Shanghai Sharing technologies Co., Ltd.

Contact:86-021-66787223

Address:No11, Lane 225, Jinxiang Road,Pudong district
Ningbo J&S Botanics Inc.

Contact:86-574-26865651

Address:529 YuanBaoShan Road, Beilun District
Nanjing Qirui Material Co., Ltd.

Contact:+86-25-52320053

Address:F4-5, #17 Building, Chuang Yi Yuan, No.6 Guanghua East Street, Nanjing, 210007 P.R.China
Chemtrade International ( China )

Contact:+86-532-86893005

Address:Rm 2-501, Huaxia Zonghe Building, No. 410 JInggangshan Road, Huangdao

Relevant to this article

Rapid access to pyrazolo[3,4-c]pyridines via alkyne annulation: Limitations of steric control in nickel-catalyzed alkyne insertions

Doi:10.1021/ol701784w
(2007)
Lewis acid-induced reaction of homophthalic anhydride with imines: A convenient synthesis of trans-isoquinolonic acids

Doi:10.1016/S0040-4039(97)10742-0
(1998)
ONO pincer type binuclear Pd(II) complex: Synthesis, crystal structure and catalytic utilization of the resulting organopalladium complex in catalytic copper-free Sonogashira coupling reaction

Doi:10.1016/j.ica.2016.07.032
(2016)
Doi:10.1021/ja01034a033
(1969)
Relationship between the structures and cytotoxic activities of 1,3,4-thiadiazolo[3,2-a]pyrimidines

Doi:10.1080/00021369.1982.10865496
(1982)
An enantioselective three-component reaction of diazoacetates with indoles and enals by iridium/iminium co-catalysis

Doi:10.1039/c5cc09918h
(2016)

Article Doi