SiO2-NHC-Cu(I): an efficient and reusable catalyst for [3+2] cycloaddition of organic azides and terminal alkynes under solvent-free reaction conditions at room temperature

Article abstract of DOI:10.1016/j.tet.2008.09.021

A novel SiO₂-NHC-Cu(I) 3b was developed and used as a highly efficient catalyst for [3+2] cycloaddition of organic azides and terminal alkynes. In the presence of SiO₂-NHC-Cu(I) 3b (1 mol %), the reactions of terminal alkynes with or