The effect of some additives on the Stille Pd0-catalyzed cross-coupling reaction

Article abstract of DOI:10.1016/0022-328X(93)80368-L

It has been found that the addition of cupric oxide to the cross-coupling reaction (Stille reaction) of 2-tributylstannylpyridine with various halobenzenes and heterocyclic halides leads to a much faster reaction and higher yields. This is also the case for the formation of thieno<3,2-h>-1,6-naphthyridine from 2-(2-trimethylstannyl-3-pyridyl)-1,3-dioxolane and t-butyl-N-(2-bromo-3-thienyl)carbamate.