Synthesis of a New Photolabile Support. 4-(2-Chloropropionyl)phenylacetamidomethyl-resin and Its Application in Solid-Phase Peptide Synthesis

Article abstract of DOI:10.1021/jo00151a015

The preparation of a new photolabile resin for solid-phase peptide synthesis is described. <4-(2-Chloropropionyl)phenyl>acetic acid was used as the handle and was obtained in three steps with an 82percent overall yield on starting from phenylacetic acid.T