Bioorganic and Medicinal Chemistry p. 1807 - 1815 (1997)
Update date:2022-08-04
Topics:
Madalengoitia, Jose S.
Tepe, Jetze J.
Werbovetz, Karl A.
Lehnert, Erich K.
Macdonald, Timothy L.
Eighteen analogues of the nonintercalative DNA topoisomerase II (topo II)-active epipodophyllotoxin-ellipticine hybrid, azatoxin, were synthesized and evaluated for their ability to induce topo II-mediated DNA strand breaks in vitro. In general, the SAR p
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(1933)
