Synthesis and cytotoxic activity of 6-(substituted-phenyl)amino-5,8- quinazolinediones

DOI: 10.1007/s00044-004-0032-8

Source and publish data:

Medicinal Chemistry Research p. 249 - 258 (2004)

Update date:2022-08-16

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Authors:

Ryu, Chung-Kyu

Yi, You-Jin

Choi, Ik Hwa

Chae, Mi Jin

Han, Ja-Young

Jung, Ok-Jai

Lee, Chong-Ock

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Article abstract of DOI:10.1007/s00044-004-0032-8

6-Arylamino-5,8-quinazolinediones were synthesized and evaluated for in vitro cytotoxic activity against human solid tumor cell lines A549, SK-OV-3, SK-MEL-2, XF498 and HCT-15. Most of the 6-arylamino-5,8-quinazolinediones exhibited potent activity against the cell lines HCT-15 and SK-MEL-2. Birkhaeuser Boston 2004.

Full text of DOI:10.1007/s00044-004-0032-8

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Product name:6,7-dichloroquinazoline-5,8-dione

Cas No:102072-83-3

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Address:Xikuang South Road, Ruicheng County , Shanxi
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