A new method for the reductive cleavage of S-S bond by the system of Cp2TiCl2/i-BuMgBr/THF and its application in synthesis of α-alkylthio carbonyl compounds

Article abstract of DOI:10.1080/00397919908086105

The reduction of disulfides by Cp₂TiCl₂/i-BuMgBr/THF led to nucleophilic sulfides [Cp₂TiSR]. This species reacted with α-bromo carbonyl compounds to give α-alkylthio carbonyl compounds in high yields.

Full text of DOI:10.1080/00397919908086105

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Synthetic Communications: An
International Journal for Rapid
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Organic Chemistry
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A New Method for the
Reductive Cleavage of S-S Bond
by the System of Cp TiCl2/i-
2
BuMgBr/THF and its Application
in Synthesis of α-Alkylthio
Carbonyl Compounds
a
a
Xian Huang & Wei-Xin Zheng
a
Department of Chemistry , Hangzhou University ,
Hangzhou, 310028, P. R. China
Published online: 17 Sep 2007.
To cite this article: Xian Huang & Wei-Xin Zheng (1999) A New Method for
the Reductive Cleavage of S-S Bond by the System of Cp TiCl2/i-BuMgBr/THF
2
and its Application in Synthesis of α-Alkylthio Carbonyl Compounds, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 29:8, 1297-1301, DOI: 10.1080/00397919908086105
To link to this article: http://dx.doi.org/10.1080/00397919908086105
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