Synthesis p. 190 - 192 (1987)
Update date:2022-08-11
Topics:
Fabiano, Emmanuel
Golding, Bernard T.
Sadeghi, Majid M.
In a convenient one-pot sequence, treatment of alcohols and α-hydroxyesters with hydrazoic acid, di-isopropyl azodicarboxylate and an excess of triphenylphosphine in tetrahydrofuran, followed by addition of water or aqueous acid, yields amines or amino-acid esters in moderate to good overall yields.
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