Improved practical synthesis of a prostaglandin and carbocyclic nucleoside synthon

Article abstract of DOI:10.1080/00397919208021086

An efficient, four step synthesis of chiral enone 2a [(+)-2,3-(isopropylidenedioxy)-4-cyclopentenone] from diol 1a (X = Cl), available from microbial oxidation of chlorobenzene, is described. This synthesis is a vast improvement over that previously reported and compares very favorably with others in the literature.

Full text of DOI:10.1080/00397919208021086

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Improved Practical Synthesis of
a Prostaglandin and Carbocyclic
Nucleoside Synthon
Tomas Hudlicky a , Michael G. Natchus a & Thomas
C. Nugent a
a Department of Chemistry , Virginia Polytechnic
Institute and State University , Blacksburg, Virginia,
24061, USA
Published online: 23 Sep 2006.
To cite this article: Tomas Hudlicky , Michael G. Natchus & Thomas C. Nugent (1992)
Improved Practical Synthesis of a Prostaglandin and Carbocyclic Nucleoside Synthon,
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 22:1, 151-157, DOI: 10.1080/00397919208021086
To link to this article: http://dx.doi.org/10.1080/00397919208021086
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