Synthesis and Spontaneous Resolution by Crystallization of R,S-(+/-)-Dimethyl(1-methyl-2-oxo-2-phenylethyl)sulphonium Bromide. X-Ray Structure and Absolute Configuration of the R-Enantiomer

Article abstract of DOI:10.1039/c39830001196

R,S-(+/-)-Dimethyl(1-methyl-2-oxo-2-phenylethyl)sulphonium bromide (3a), obtained from 1-phenylpropanone by bromination with t-butyl bromide-dimethyl sulphoxide and further reaction with dimethyl sulphide, undergoes spontaneous resolution of its two enantiomers upon crystallization, as demonstrated by a single crystal X-ray analysis and assignment of absolute configuration (R).

Full text of DOI:10.1039/c39830001196

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