
Journal of the Chemical Society. Chemical communications p. 1196 - 1197 (1983)
Update date:2022-08-30
Topics:
Dossena, Arnaldo
Marchelli, Rosangela
Armani, Elisabetta
Fava, Giovanna Gasparri
Belicchi, Marisa Ferrari
R,S-(+/-)-Dimethyl(1-methyl-2-oxo-2-phenylethyl)sulphonium bromide (3a), obtained from 1-phenylpropanone by bromination with t-butyl bromide-dimethyl sulphoxide and further reaction with dimethyl sulphide, undergoes spontaneous resolution of its two enantiomers upon crystallization, as demonstrated by a single crystal X-ray analysis and assignment of absolute configuration (R).
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