A NEW AND FACILE SYNTHESIS OF N-SUBSTITUTED PYRROLIDINE OF AMINES WITH AQUEOUS SUCCINALDEHYDE USING TETRACARBONYLHYDRIDOFERRATE, HFe(CO)4(1-), AS A HIGHLY SELECTIVE REDUCING AGENT.

Article abstract of DOI:10.1016/S0040-4020(01)87426-3

Ethanolic tetracarbonylhydridoferrate combined with aqueous succinaldehyde is very efficient for the selective transformation of an amino group into a pyrrolidine ring.A large variety of both aliphatic and aromatic amines react with aqueous succinaldehyde in the presence of tetracarbonylhydridoferrate at room temperature under carbon monoxide to give the corresponding N-alkyl- and N-arylpyrrolidines in good to excellent yields.