Ring opening of fluoroalkyl-containing α,β-epoxyketones by aromatic amines

Article abstract of DOI:10.1007/BF00717347

Aromatic amines cause α,β-epoxyketones containing a β-fluoroalkyl group to undergo ring opening at the α-position to give α-amino-β-hydroxyketones. - Key words: fluoroalkyl-containing α,β-epoxyketones; epoxide ring opening; fluoroalkyl-containing α-amino-