New chiral catalysts for the highly enantioselective addition of diethylzinc to aldehydes

Article abstract of DOI:10.1016/S0040-4039(96)02027-8

Optically active amino thioacetate derivatives of (+)-norephedrine were found to act as effective catalysts for enantioselective addition of diethylzinc to aldehydes. This reaction provided optically active secondary alcohols with e.e. of up to >99%.