Pyridoxal-catalyzed release of nucleotides

Article abstract of DOI:10.1080/15257779908041635

The synthesis of phosphoric esters linking the 5' alcohol of thymidine to the alcohol moiety of L-serine derivatives is reported, together with the pyridoxal-catalyzed β-elimination reaction releasing thymidylate from such compounds. The process was extended to the release of thymidine di- and tri- phosphate.