A palladium-catalyzed carbonylative route to primary amides

Article abstract of DOI:10.1016/S0040-4039(98)00259-7

The palladium-catalyzed reaction of aryl and vinyl iodides and triflates with carbon monoxide in the presence of hexamethyldisilazane followed by hydrolytic work-up affords aromatic and α,β-unsaturated primary amides in good to high yields under relatively mild conditions.