Efficient enantioselective synthesis of methyl esters of α-unsubstituted β-hydroxy acids via asymmetric aldol-type addition of chiral boron enolates of (methylthio)acetic acid to aldehydes

Article abstract of DOI:10.1055/s-1996-4365

The aldol-type addition of chiral boron enolates of (methylthio)acetic acid to various aldehydes gives α-(methylthio)-β-hydroxy acids stereoselectively and with good yields. The desulfenylation of methyl esters of the condensation adducts allows methyl es