Chemical and Pharmaceutical Bulletin p. 2576 - 2578 (1992)
Update date:2022-08-30
Topics:
Yokoyama
Sunohara
Fujie
A new crystalline complex composed of docosanoic acid and nicotinamide (NAA) was prepared. The release of NAA from the complex in an aqueous medium was found to be ON-state above 37°C and OFF-state below 37°C, suggesting that the release behavior is applicable to a temperature-respondent drug delivery system
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