Design, synthesis, and in vitro antiproliferative and kinase inhibitory effects of pyrimidinylpyrazole derivatives terminating with arylsulfonamido or cyclic sulfamide substituents

DOI: 10.1080/14756366.2016.1190715

Source and publish data:

Journal of Enzyme Inhibition and Medicinal Chemistry p. 111 - 122 (2016)

Update date:2022-08-23

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Authors:

Gamal El-Din, Mahmoud M.

El-Gamal, Mohammed I.

Abdel-Maksoud, Mohammed S.

Yoo, Kyung Ho

Baek, Daejin

Choi, Jungseung

Lee, Huiseong

Oh, Chang-Hyun

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Article abstract of DOI:10.1080/14756366.2016.1190715

A novel series of substituted pyrimidine compounds bearing N-phenylpyrazole and terminating with aryl and cyclic sulfonamido moiety were designed, synthesized, and evaluated in vitro as antiproliferative agents against a panel of 53 cell lines of differen

Full text of DOI:10.1080/14756366.2016.1190715

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