A Novel Enantiospecific Synthesis of (S)-(-)-Methyl 6,8-Dihydroxyoctanoate, a Precursor of (R)-(+)-α-Lipoic Acid

DOI: 10.1039/c39900000729

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 729 - 730 (1990)

Update date:2022-08-29

Topics:

Authors:

Dasaradhi, L.

Fadnavis, N. W.

Bhalerao, U. T.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39900000729

(S)-(-)-Methyl 6,8-dihydroxyoctanoate has been synthesised, with stereocontrolled reduction of methyl 8,8-dimethyl-6-oxo-octanoate using immobilised Bakers yeast as a key step.

Full text of DOI:10.1039/c39900000729

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:methyl (6S)-6,8-dihydroxyoctanoate

Cas No:116349-04-3

R&D Labs maybe for 116349-04-3

Hangzhou jls Flame Retardants Chemical Co.,Ltd

Contact:+86-571-87250387/87250386

Address:MOGANSHAN RODA 1418# SHANGCHENG INDUSTRIAL PARK
LIAOYANG WANRONG CHEMICALS COMPANY LIMITED

Contact:86-419-2390789

Address:XINLI VILLAGE , DONG NINGWEI COUNTY,TAIZIHE DISTRICT, LIAOYANG , LIAONING
Wuxi Forest Biological Co.,Ltd

Contact:+86-510-81602300

Address:Room 317,Building D, No.159 middle Chengjiang Road,Jiangyin Wuxi city.
Taizhou Crene Biotechnology co.ltd

Contact:86-576-88813233 88205808

Address:Economic Developed Zone of Taizhou Zhejiang China
ZHANGJIAGANG FREE TRADE ZONE YONG HAN INTERNATIONAL TRADING CO., LTD(expird)

Contact:86 512 57910558

Address:qianjin M road

Relevant to this article

Two-photon laser-induced reaction of 1,8-bis(halomethyl)naphthalenes from different excited states and transient targeting of its intermediate by time-delayed, two-color photolysis and argon ion laser-jet photolysis techniques

Doi:10.1021/ja962884l
(1997)
Synthesis of {2,3-dihydro-7-halopyrrolo-[(2,1-b)]-quinazolin-9-(1h)-one and 2,3-dihydro-5,7-dihalopyrrolo-[(2,1-b)]-quinazolin-9-(1h)-one}: New analogs of deoxyvasicinone

Doi:10.1080/00397911.2010.534228
(2012)
Human intestinal bacteria mediate reduction of the N-oxides of isoline and monocrotaline to the corresponding parent alkaloids

Doi:10.14233/ajchem.2013.13283
(2013)
Efficient synthesis of α-aryl-/heteroaryl-substituted β-amino acids via Ni(II) complex through the Suzuki coupling reaction

Doi:10.1021/jo900469d
(2009)
Vacuum-ultraviolet photochemically initiated modification of polystyrene surfaces: Chemical changes

Doi:10.1562/2004-11-30-RA-387R.1
(2005)
A mild and highly efficient one-pot three-component reaction for carbon-sulfur bond formation catalyzed by potassium tert-butoxide

Doi:10.1016/j.cclet.2011.05.015
(2011)

Article Doi