A new, simple procedure for the preparation of 8-methoxy-2-tetralone

Article abstract of DOI:10.1080/00397919508011824

8-Methoxy-2-tetralone (6) can be easily prepared in approximately 50% overall yield starting from 2-bromophenylacetic acid (1), utilizing a Friedel-Crafts acylation/cyclization, ketone protection, copper(I)-catalyzed methoxylation of the aromatic bromide

Full text of DOI:10.1080/00397919508011824

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A New, Simple Procedure
for the Preparation of 8-
Methoxy-2-Tetralone
a
a
Sunkyung Lee , Stewart P. Frescas & David E.
a
Nichols
a
Department of Medicinal Chemistry and
Pharmacognosy , School of Pharmacy and Pharmacal
Sciences, Purdue University , West Lafayette, IN,
47907
Published online: 16 Feb 2007.
To cite this article: Sunkyung Lee , Stewart P. Frescas & David E. Nichols (1995)
A New, Simple Procedure for the Preparation of 8-Methoxy-2-Tetralone, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 25:18, 2775-2780, DOI: 10.1080/00397919508011824
To link to this article: http://dx.doi.org/10.1080/00397919508011824
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