Journal of Heterocyclic Chemistry p. 1263 - 1268 (1998)
Update date:2022-08-11
Topics:
Almena, Ines
Diez-Barra, Enrique
De La Hoz, Antonio
Ruiz, Juliana
Sanchez-Migallon, Ana
Elguero, Jose
The use of sodium hydrogen carbonate under solvent-free conditions and microwave irradiation is by far the best method for N-alkylating pyrazoles. The yields are good and the method is devoid of side reactions (quaternization, isomerization, hydrogen hali
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