Tetrahedron Letters p. 273 - 274 (1994)
Update date:2022-08-17
Topics:
Hayes
Hayes, Jerome F.
Mitchell
Mitchell, Michael B.
Procter
Procter, Carry
A novel synthesis of a tetra-substituted imidazole is described. A key feature of the synthesis is the regioselective deprotonation of picolylpyrrolidinone 3 and the efficient reaction of this anion with an aryl nitrile to give the pyrrolidinoimidazole nu
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