A Convenient Synthesis of (2S,4R)-1-Acetoxy-2,4-O-Isopropylidene-1,2,5-Pentanetriol by Using Lipase Catlyzed Regio- and Enantioselective Reactions

Article abstract of DOI:10.1246/cl.1993.1529

(2S,4R)-1-Acetoxy-2,4-O-isopropylidene-1,2,5-pentanetriol, which is expected to be intermediate for a synthesis of an inhibitor of HMG-CoA reductase, was synthesized by lipase catalyzed regio- and enantioselective transesterifications.