Tetrahedron p. 14127 - 14130 (1997)
Update date:2022-08-11
Topics:
Martinez, M. Montserrat
Onega, M. Gabriela
Tellado, M. Fe
Seijas, Julio A.
Vazquez-Tato, M. Pilar
Phtalhides are prepared from o-vinylphenyloxazolines in one pot reaction by 1,6-conjugate addition or alkyllithium and trapping of the benzylic anion with MoOPH, followed by hydrolysis with aqueous oxalic acid. This method was applied to the syntheses of two natural products: chuangxinol and 3-n-butylphthalide.
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Doi:10.1039/c7dt01323j
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