148. Formation of N-Hydroxy-amines of Spin Labeled Nucleosides for 1H-NMR. Analysis

Article abstract of DOI:10.1002/hlca.19800630609

Amine-oxide radical 1a was efficiently converted to the corresponding N-hydroxy-amine 2a with sodium dithionite in acetone/water.This reaction was used to develop a procedure for monitoring the NMR. spectra of sodium dithionite reduced amine-oxide radicals and of novel reduced amine-oxide-labeled nucleosides.