Preparation of α-halo-F-2-ketones and F-2-ketones via fluorination of α,α-dihalo-F-2-ketones

Article abstract of DOI:10.1016/S0022-1139(00)80488-1

Fluorination of α,α-dichloro-F-2-ketones with antimony pentafluoride provided excellent yields of α-chloro-F-2-ketones and F-2-ketones regioselectively.However, fluorination of α,α-dibromo-F-2-ketones with antimony pentafluoride gave a mixture of α-bromo-F-2-ketones and F-2-ketones.