Chemistry Letters p. 693 - 694 (1999)
Update date:2022-08-29
Topics:
Dean, Mariangela
Fantin, Giancarlo
Fogagnolo, Marco
Medici, Alessandro
Pedrini, Paola
Poli, Silvia
The microbial 7-OH epimerisation of cholic and chenodeoxycholic acids with Xanthomonas maltophilia CBS 827.97 to ursocholic and ursodeoxycholic acids with scarsity of oxygen is described. With normal pressure of oxygen the 7-ketocholic and the 7-ketochenodeoxycholic acids are obtained. No biotransformation is achieved in anaerobic conditions.
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