Tetrahedron Letters p. 167 - 170 (1993)
Update date:2022-08-17
Topics:
Batchelor
Gillespie
Golec
Hedgecock
The use of the Dess-Martin reagent for the oxidation of β-hydroxy and β-ketoamides, esters and ketones to the corresponding tricarbonyl compounds is reported. The method is shown to be applicable to the synthesis of analogues of the immunosuppressant FK506.
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