A novel DMAP-promoted oxazolidinethione deacylation. Application for the direct conversion of the initial chiral thioimide aldols to various ester protecting groups.

DOI: 10.1016/S0040-4039(99)00710-8

Source and publish data:

Tetrahedron Letters p. 4197 - 4198 (1999)

Update date:2022-08-30

Topics:

Authors:

Su, Dah-Wei

Wang, Ying-Chuan

Yan, Tu-Hsin

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Article abstract of DOI:10.1016/S0040-4039(99)00710-8

DMAP (4-(dimethylamino)pyridine) promoted nucleophilic cleavage of the initial chiral thioimide aldols can be directed to form various ester protecting groups without causing racemization of the newly created stereocenters.

Full text of DOI:10.1016/S0040-4039(99)00710-8

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