Synthesis of (-)-6-hydroxyshikimic acid from ((5S,6R)-5,6-dihydroxy-1,3-cyclohexadienyl)methanenitrile

DOI: 10.1016/0957-4166(96)00064-X

Source and publish data:

Tetrahedron Asymmetry p. 691 - 698 (1996)

Update date:2022-08-28

Topics:

Authors:

Tran, Chuong Hao

Crout, David H.G.

Errington, William

Whited, Gregory M.

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Article abstract of DOI:10.1016/0957-4166(96)00064-X

A six step synthesis of (-)-6-hydroxyshikimic acid 2 has been developed starting from ((5S,6R)-5,6-dihydroxy-1,3-cyclohexadienyl)methanenitrile 3, produced by biotransformation of cyanobenzene by the enzyme toluene dioxygenase.

Full text of DOI:10.1016/0957-4166(96)00064-X

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