Direct synthesis of amphiphilic α-, β-, and γ-cyclodextrins

Article abstract of DOI:10.1080/07328309608005692

The clean one step synthesis of the amphiphilic α-, β-, and γ-cyclodextrins starting from per-(6-bromo-6-deoxy)-α-, -β-, and -γ-cyclodextrins is described. The role of the lipophilic tail is played by various aryl groups (phenyl, p-bromophenyl, p-O-butoxyphenyl, p-pentylphenyl, and o-, m-, and p-nitrophenyl) linked by a thioether bridge to the position C-6 of each glucopyranose unit. The yields of the S-alkylation reactions were very high (85-95%).

Full text of DOI:10.1080/07328309608005692

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Journal of Carbohydrate Chemistry
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Direct Synthesis of Amphiphilic α-, β-,
and γ-Cyclodextrins
Kazimierz Chmurski a , Antony W. Coleman c & Janusz Jurczak a b
a Institute of Organic Chemistry, Polish Academy of Sciences ,
Kasprzaka 44/52, 01-224, Warsaw, Poland
b Department of Chemistry , Warsaw University , Pasteura 1, 02-093,
Warsaw, Poland
c Institute de Biologie et Chimie des Proteines , CNRS UPR412, 7
passage du Vercors, Lyon, F69367, France
Published online: 22 Aug 2006.
To cite this article: Kazimierz Chmurski , Antony W. Coleman & Janusz Jurczak (1996) Direct
Synthesis of Amphiphilic α-, β-, and γ-Cyclodextrins, Journal of Carbohydrate Chemistry, 15:7,
787-796, DOI: 10.1080/07328309608005692
To link to this article: http://dx.doi.org/10.1080/07328309608005692
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