New One-Pot Preparation of α,β-Unsaturated Carboxylic Acid Esters from Carbonyl Compounds

Article abstract of DOI:10.1055/s-1988-27628

A series of α,β-unsaturated carboxylic acid esters have been prepared by the reaction of carbonyl compounds with alkoxy acetylide anions generated in situ from the readily available α-chloroacetaldehyde dialkyl acetals in the presence of lithium diisopropylamide, followed by aqueous acidic work-up.