Journal of Medicinal Chemistry p. 4449 - 4454 (1994)
Update date:2022-08-11
Topics:
Nugent
Schlachter
Murphy
Dunn
Staite
Galinet
Shields
Wu
Aspar
Richard
A study of the decomposition of the pyrazoline bisphosphonate ester 2 identified 3 as the sole bisphosphonate component. Evaluation in a delayed- type hypersensitivity granuloma model of chronic inflammation in mice (DTH- GRA) showed 3 to be a potent inhi
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