Reductive methylation of secondary amines containing reducible, hydrolyzable and sterically hindered groups

Article abstract of DOI:10.1080/00397910008086975

Aliphatic secondary amines, including those that are sterically hindered, undergo reductive methylation under mild conditions in high yield using formaldehyde and sodium phosphite solution without reducing or hydrolyzing ethynyl, ester or cyano groups.

Full text of DOI:10.1080/00397910008086975

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Reductive Methylation of
Secondary Amines Containing
Reducible, Hydrolyzable and
Sterically Hindered Groups
a
a
Bruce A. Davis & David A. Durden
a
Neuropsychiatry Research Unit , A114 Medical
Research Building, University of Saskatchewan , 103
Wiggins Road, Saskatoon, Saskatchewan, Canada ,
S7N 5E4
Published online: 04 Dec 2007.
To cite this article: Bruce A. Davis & David A. Durden (2000) Reductive Methylation
of Secondary Amines Containing Reducible, Hydrolyzable and Sterically Hindered
Groups, Synthetic Communications: An International Journal for Rapid Communication
of Synthetic Organic Chemistry, 30:18, 3353-3362, DOI: 10.1080/00397910008086975
To link to this article: http://dx.doi.org/10.1080/00397910008086975
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