Bioorganic and Medicinal Chemistry Letters p. 2165 - 2168 (1997)
Update date:2022-08-30
Topics:
Kokotos, George
Theodorou, Vassiliki
Tzougraki, Chryssa
Deforce, Dieter L.D.
Van Den Eeckhout, Elfreide G.
A number of cis-dichloro[bis(aminocoumarin)platinum(II) complexes have been synthesized and evaluated for their in vitro cytotoxicity against Caco-2T cells. The complex with 7-amino-4-trifluoromethylcoumarin as ligand has been found to be the most active (IC50 10 μ/ml) in this study.
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