Steroids p. 230 - 233 (1993)
Update date:2022-08-11
Topics:
Tuckey, Robert C.
Cameron, Kathryn J.
(22R)-20α,22-Dihydroxycholesterol is the second intermediate in the conversion of cholesterol to pregnenolone by cytochrome P450scc in steroidogenic tissues.We report a rapid method for the enzymatic synthesis of (22R)-20α,22-dihydroxycholesterol from (22R)-20-hydroxycholesterol using mitochondria from the human placenta. (Steroids 58:230-233, 1993) Keywords: steroids; cytochrome P450scc; placental mitochondria; (22R)-20α,22-dihydroxycholesterol; (22R)-22-hydroxycholesterol; pregnenolone
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