
Tetrahedron Letters p. 3511 - 3514 (1984)
Update date:2022-08-11
Topics:
Pinnell, R. P.
Khune, G. D.
Khatri, N. A.
Manatt, S. L.
Chloromethyl methyl ether-stannic chloride treatments of toluene, ethylbenzene, isopropylbenzene and tert-butyl benzene afforded respectively, 26.5, 16.8, 5.5 and 2.5percent orthoproducts.No meta-products could be detected (less than 0.5percent).Similar chloroalkylation of linear polystyrenes followed by conversion of the chloromethyl groups to hydroxylmethyl, yielded products possessing 5.0 +/- .3percent ortho-substitution.
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