Stereospecific coordination of L-hydroxyproline esters with triosmium clusters

Article abstract of DOI:10.1007/BF00707232

The reactions of cluster (μ-H)Os3(CO)10(μ-OH) with ethyl and isopropyl esters of L-oxyproline were studied.In the presence of Me3NO intermediate complex (μ-H)Os3(CO)9(μ-OH)L (L - isopropyl ester of L-oxyproline) is formed, which slowly converts to the more stable cluster .Cluster complexes containing chelate-bridging heterocycles were also obtained by heating (μ-H)Os3(CO)10(μ-OH) with esters of L-oxyproline.In both cases, only one of the possible diastereomeric complexes (R = Et, Prⁱ) is formed, which indicates that the reactions are stereospecific.Based on analysis of Dreiding's models, an attempt to determine the absolute configuration of the obtained clusters was made. - Keywords: triosmium clusters, L-hydroxyproline esters, stereospecific coordination