Solid-phase synthesis of glycopeptides: Synthesis of N(α)-fluorenylmethoxycarbonyl L-asparagine N(β)-glycosides

Article abstract of DOI:10.1016/0040-4039(91)80802-D

It was found that crude 1-glycosylamines, prepared with satured aqueous NH₄HCO₃ from reducing sugars, can be coupled with Fmoc-Asp(OPfp)-O(t)Bu in N,N-dimethylformamide-water mixtures. Purification and removal of the (t)Bu group resu