Two-Carbon Elongation/Annulation of Alcohols to Nitriles

DOI: 10.1016/00404-0399(50)11252-

Source and publish data:

Tetrahedron Letters p. 5691 - 5694 (1995)

Update date:2022-08-17

Topics:

Authors:

Lai, Jing-Yu

Yu, Jurong

Hawkins, R. David

Falck, J. R.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/00404-0399(50)11252-

Alcohols were replaced by a two-carbon nitrile unit in good to excellent yields via dehydrative alkylation with (phenylsulfonyl)acetonitrile under modified Mitsunobu conditions followed by desulfonylation using magnesium.Diols and haloalcohols furnished cycloalkylnitriles.

Full text of DOI:10.1016/00404-0399(50)11252-

Products guided by the article

Product name:1-(phenylsulfonyl)cyclopentanecarbonitrile

Cas No:170803-75-5

R&D Labs maybe for 170803-75-5

Tianjin Ji Ping Jia Chemical Co., Ltd.

Contact:18622448868

Address:tianjin
Shanghai Yudiao Chemistry Technology Co.,Ltd

Contact:0086-18964703211

Address:Building NO.5, NO.218,Rongtian Road,ganxiang town,Jinshan District,shanghai,201518,china
KAIYUAN CHEMICAL COMPANY LIMITED.

website:http://www.kaiyuanchem.com

Contact:+86-22-59891255/66/77

Address:B-2205, Kuangshi International Building, Yingbin Road, XiangLuo Bay Business District, Binhai New area, Tianjin, China.
ZUNYI CITY BEI YUAN CHEMICAL CO., LTD

website:http://www.china-beiyuan.com

Contact:+86-851-27751258

Address:Shawan Town, Huichuan District, Zunyi City, Guizhou Province, China
Shantou Baokang Pharmaceutical Co., Ltd.

Contact:+86-754-88873487

Address:5/F B Block Huangshan Bldg Huangshan Rd Shantou

Relevant to this article

Rh-Catalyzed Reactions of 3-Diazoindolin-2-imines: Synthesis of Pyridoindoles and Tetrahydrofuropyrroloindoles

Doi:10.1021/acs.orglett.5b01943
(2015)
Hyperbranched Polymers with High Degrees of Branching and Low Dispersity Values: Pushing the Limits of Thiol-Yne Chemistry

Doi:10.1021/acs.macromol.6b00132
(2016)
Synthesis and antiproliferative activity of some new DNA-targeted alkylating pyrroloquinolines

Doi:10.1016/j.bmc.2003.10.057
(2004)
Cell Factory Design and Optimization for the Stereoselective Synthesis of Polyhydroxylated Compounds

Doi:10.1002/cbic.201700464
(2018)
New heteroaromatic azo compounds based on pyridine, isoxazole, and benzothiazole for efficient and highly selective amidation and mono-N-benzylation of amines under Mitsunobu conditions

Doi:10.1246/bcsj.20090269
(2010)
Phytochemical characterization and biological activity of secondary metabolites from three Limonium species

Doi:10.1007/s00044-017-1973-z
(2017)

Article Doi