The Chemistry of Ethyl 3-(2-Ethoxy-2-oxoethyl)-1 H -indole-2-carboxylate: Synthesis of Pyrimido[4,5- b ]indoles and Diethyl 4-Hydroxyquinoline-2,3-dicarboxylate via Intramolecular Cyclizations

Article abstract of DOI:10.1055/s-0036-1588119

We report the synthesis of a new series of 2-oxo-1,2,4,9-tetrahydro-3H-pyrimido[4,5-b]indole derivatives and diethyl 4-hydroxyquinoline-2,3-dicarboxylate starting from ethyl 3-(2-ethoxy-2-oxoethyl)-1H-indole-2-carboxylate. Intramolecular cyclization forme