An efficient general synthesis of 1-amino-2-naphthalenecarboxylic acid derivatives based on a tandem conjugate addition-enolate nitrile coupling sequence

DOI: 10.1246/cl.1996.25

Source and publish data:

Chemistry Letters p. 25 - 26 (1996)

Update date:2022-08-17

Topics:

Authors:

Kobayashi, Kazuhiro

Takada, Keiichiro

Tanaka, Hiroto

Uneda, Tomokazu

Kitamura, Tomohide

Morikawa, Osamu

Konishi, Hisatoshi

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Article abstract of DOI:10.1246/cl.1996.25

Reaction of o-(α-lithioalkyl)benzonitriles with α,β-unsaturated carboxylic acid derivatives produced 1-amino-3,4-dihydro-2-naphthalenecarboxylic acid derivatives through the tandem conjugate addition-enolate nitrile coupling sequence, which in turn were c

Full text of DOI:10.1246/cl.1996.25

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