Angewandte Chemie - International Edition in English p. 525 - 527 (1997)
Update date:2022-08-22
Topics:
Nicolaou
Sarabia
Ninkovic
Yang
This highly convergent and practical total synthesis of the antitumor agent epothilone A uses a macrolactonization as the key step. The strategy may provide access to a variety of epothilones desirable for biological screening.
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Doi:10.1021/ja980792l
(1998)Doi:10.1021/jo991538u
(2000)Doi:10.1023/A:1009518127038
(1999)Doi:10.1016/S0040-4039(00)97791-8
(1990)Doi:10.1016/0040-4039(96)00912-4
(1996)Doi:10.1016/S0040-4039(00)93543-3
(1991)
