Synthetic studies on naturally occurring coumarins. I. A convenient synthesis of 5,8-dimethoxy- and 7,8-dimethoxycoumarins

DOI: 10.1248/cpb.40.1770

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1770 - 1772 (1992)

Update date:2022-08-17

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Authors:

Ishii Ishii

Kenmotsu

Dopke Dopke

Harayama

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Article abstract of DOI:10.1248/cpb.40.1770

The coumarin isolated from Artemisia carvifolia Wall was proved synthetically to be 7,8-dimethoxycoumarin and not 5,8-dimethoxycoumarin as previously proposed. 3,4-Dimethoxy- and 3,6-dimethoxysalicylaldehydes gave the corresponding coumarins in good yield by the method using phosphorane reagent in N,N-diethylaniline under reflux.

Full text of DOI:10.1248/cpb.40.1770

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