One-pot synthesis of N-substituted pyrroles catalyzed by polystyrene-supported aluminum chloride as a reusable heterogeneous Lewis acid catalyst

Article abstract of DOI:10.1002/hc.20661

A convenient and efficient procedure is presented for the one-pot synthesis of N-substituted pyrroles by condensation of 2,5-hexandione and amines or diamines in the presence of cross-linked polystyrene-supported aluminum chloride (PS/AlCl₃) as a highly active and reusable heterogeneous Lewis acid catalyst. This polymeric solid acid catalyst is stable and can be easily recovered and reused without appreciable change in its efficiency.