The hydrogenation of alpha-hydroxymethylene-ketone derivatives to alpha-hydroxymethyl-ketone derivatives with a cell-free system of Streptomyces cinereocrocatus.

DOI: 10.1248/cpb.37.502

Source and publish data:

Chemical and pharmaceutical bulletin p. 502 - 505 (1989)

Update date:2022-08-28

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Authors:

Oda Oda

Sato Sato

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Article abstract of DOI:10.1248/cpb.37.502

2',3'-Dihydro-5'-formylgriseofulvin (3), oxymetholone (5), and 3 beta-acetoxy-16-acetoxymethylene-5-androsten-17-one (9) were used as the substrates of a cell-free system from Streptomyces cinereocrocatus NRRL 3443. The results indicated that S. cinereocrocatus contains enzymatic activities which reduce the above three alpha-hydroxymethylene-ketones to the corresponding alpha-hydroxymethyl-ketones.

Full text of DOI:10.1248/cpb.37.502

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