Use of tetrahydro-2H-1,3-oxazinones as aminopropylation agents

Article abstract of DOI:10.1080/00397919308011220

Treatment of tetrahydro-2H-1,3-oxazin-2-one (1) or the 3-methyl derivative 2 with aniline salts or thiophenols at 180°C affords the corresponding N-aryl-1,3-propanediamines 3 or 3-(arylthio)propanamines 4 in good yields.

Full text of DOI:10.1080/00397919308011220

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Synthetic Communications: An
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Use of Tetrahydro-2H-1,3-
Oxazinones as
Aminopropylation Agents
a
a
Graham S. Poindexter & Karen M. Strauss
a
Bristol-Myers Squibb Pharmaceutical Institute, 5
Research Parkway, Wallingford, CT 06492-7660
Version of record first published: 24 Sep 2006.
To cite this article: Graham S. Poindexter & Karen M. Strauss (1993): Use
of Tetrahydro-2H-1,3-Oxazinones as Aminopropylation Agents, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 23:9, 1329-1338
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