New opportunities for α-ketenyl radicals in ring synthesis

Article abstract of DOI:10.1016/S0040-4039(98)01479-8

Unsaturated acyl radicals are shown to be useful precursors to α- ketenyl radical intermediates which are then used in the synthesis of aromatic cyclic ketones. The behaviour of cyclopropyl acyl radicals is also described, in particular the 8-endo-trig cyclisation of 3-substituted cyclopropyl acyl radicals to give bicyclo[6.1.0]nonanones, and in the synthesis of cyclic enol lactones.