REGIOSPECIFIC ADDITION OF ORGANOCOPPER REAGENTS TO α,β-UNSATURATED ESTERS

Article abstract of DOI:10.1016/S0040-4039(00)84727-9

Mixed cuprates ArSCu(RMgX)n add rapidly to crotonates and cinnamates to give high yields of Michael adducts.Cuprates of methyl, ethyl, isopropyl, t-butyl, phenyl and vinyl were used.Crotonates give much higher yields of adducts with cuprates using 2-methoxythiophenoxide as a ligand than with those using thiophenoxide.