Tetrahedron Letters p. 2227 - 2230 (1999)
Update date:2022-08-29
Topics:
Linn, James A.
Gerritz, Samuel W.
Handlon, Anthony L.
Hyman, Clifton E.
Heyer, Dennis
The solid phase synthesis of 1,3,5-trisubsituted pyridin-2-ones is reported via selective 1NH-alkylation of 3-amino-5-carbomethoxy-1H-pyridin- 2-one with a solid-supported halo-acid. Coupling of an acid to solid- supported 3-aminopyridinone was
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